Do humans count?
Heheh. Um. There are times when the species are very vastly different that understanding and communication are virtually impossible.
The jury is very much out on the Hyperspace-native species known through onomatopoeic nomenclature as the Xyrak’l. Nobody knows if they’re cogniscent, cusp-cogniscent, or non-cogniscent.
But they are big enough to crush a standard passenger liner, so the general consensus is to leave them to their own business.
And then there’s the vary rare cases where a colony is encountered where the tech and society level has backslid to the level of gatherer-hunter or worse.